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Description

Glycosyl derivatives of dopamine and L-dopa as anti-Parkinson prodrugs: synthesis, pharmacological activity and in vitro stability studies

Xiao et al., 2012) Briefly, mice were fed with on rodent chow containing 0.2% (w/w) cuprizone (bis-cyclohexanone oxaldihydrazone, Sigma #14690-100G) for different durations up to 5 weeks before sampling for the detection of demyelination and tracing of the OL lineage cell dynamics in the demyelination courses